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Douglas W Losordo Selected Research

Peripheral Nervous System Diseases (PNS Diseases)

1/2007Therapeutic angiogenesis inhibits or rescues chemotherapy-induced peripheral neuropathy: taxol- and thalidomide-induced injury of vasa nervorum is ameliorated by VEGF.
5/2005Antiangiogenesis mediates cisplatin-induced peripheral neuropathy: attenuation or reversal by local vascular endothelial growth factor gene therapy without augmenting tumor growth.

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Douglas W Losordo Research Topics

Disease

25Myocardial Infarction
02/2016 - 06/2004
22Ischemia
01/2022 - 07/2002
14Myocardial Ischemia (Ischemic Heart Diseases)
06/2013 - 01/2002
13Cardiovascular Diseases (Cardiovascular Disease)
10/2020 - 05/2005
9Infarction (Infarctions)
01/2017 - 04/2002
7Heart Failure
01/2018 - 07/2003
7Chronic Limb-Threatening Ischemia
04/2017 - 01/2005
6Fibrosis (Cirrhosis)
07/2012 - 04/2005
5Left Ventricular Dysfunction
01/2017 - 01/2009
5Wounds and Injuries (Trauma)
01/2016 - 05/2006
4Corneal Neovascularization
02/2012 - 08/2002
3Coronary Artery Disease (Coronary Atherosclerosis)
01/2022 - 09/2004
3Pain (Aches)
04/2015 - 04/2013
3Peripheral Arterial Disease
04/2015 - 10/2009
3Inflammation (Inflammations)
04/2015 - 01/2009
3Hypoxia (Hypoxemia)
12/2014 - 07/2006
3Diabetic Neuropathies (Diabetic Neuropathy)
07/2005 - 07/2003
2ST Elevation Myocardial Infarction
01/2017 - 08/2011
2Hyperplasia
01/2016 - 10/2006
2Vascular System Injuries
01/2016 - 09/2009
2Necrosis
09/2014 - 02/2009
2Hypertension (High Blood Pressure)
09/2013 - 09/2009
2Spinocerebellar Ataxias (Spinocerebellar Ataxia)
01/2013 - 07/2012
2Heart Diseases (Heart Disease)
07/2012 - 05/2011
2Atherosclerosis
03/2010 - 01/2007
2Neointima
09/2009 - 07/2004
2Vascular Diseases (Vascular Disease)
02/2007 - 03/2006
2Peripheral Nervous System Diseases (PNS Diseases)
01/2007 - 05/2005
2Neoplasms (Cancer)
05/2005 - 09/2004
2Peripheral Vascular Diseases (Peripheral Vascular Disease)
01/2005 - 01/2002
1Microvascular Angina (Cardiac Syndrome X)
01/2022
1Acute Coronary Syndrome
01/2016
1Vascular Ring
09/2013
1Intermittent Claudication
04/2013
1Cardiomyopathies (Cardiomyopathy)
03/2013
1Reperfusion Injury
01/2013
1Cardiac Arrhythmias (Arrythmia)
11/2012
1Teratoma (Teratoid Tumor)
07/2012

Drug/Important Bio-Agent (IBA)

17Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2014 - 04/2002
9erucylphosphocholineIBA
06/2013 - 08/2002
7CytokinesIBA
01/2016 - 09/2004
5Interleukin-10 (Interleukin 10)IBA
01/2016 - 10/2006
5DNA (Deoxyribonucleic Acid)IBA
07/2012 - 03/2003
4Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
12/2014 - 09/2004
4plerixaforFDA Link
01/2013 - 06/2010
3omega-Chloroacetophenone (Mace)IBA
01/2018 - 11/2012
3Therapeutic UsesIBA
04/2017 - 02/2007
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
01/2016 - 02/2007
3Type II Tumor Necrosis Factor ReceptorsIBA
04/2015 - 02/2007
3Peptides (Polypeptides)IBA
09/2014 - 08/2011
3Granulocyte Colony-Stimulating Factor (G-CSF)IBA
01/2014 - 06/2007
3Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
06/2013 - 03/2006
3Messenger RNA (mRNA)IBA
03/2012 - 07/2003
3CholesterolIBA
03/2010 - 07/2005
2InterleukinsIBA
12/2015 - 01/2009
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
12/2014 - 02/2012
2CXCR4 Receptors (CXCR4 Receptor)IBA
01/2013 - 03/2012
2Histones (Histone)IBA
07/2012 - 06/2008
2Chemokine CXCL12IBA
03/2012 - 05/2009
2EnzymesIBA
08/2011 - 06/2007
2Estradiol (Delestrogen)FDA LinkGeneric
02/2009 - 03/2006
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2007 - 07/2005
2Proteins (Proteins, Gene)FDA Link
11/2004 - 07/2003
1Pharmaceutical PreparationsIBA
08/2017
1Cardiovascular AgentsIBA
08/2017
1Wnt ProteinsIBA
02/2016
1ChemokinesIBA
01/2016
1Semaxinib (SU5416)IBA
12/2014
1salicylhydroxamic acid (SHAM)IBA
09/2013
1Nitric Oxide (Nitrogen Monoxide)FDA Link
09/2013
1Cell-Penetrating PeptidesIBA
09/2013
1Cyclic GMP-Dependent Protein Kinase Type IIBA
09/2013
1Ethanol (Ethyl Alcohol)IBA
06/2013
1Estrogens (Estrogen)FDA Link
06/2013
1MethyltransferasesIBA
07/2012
1Histone Deacetylases (Histone Deacetylase)IBA
07/2012
1Valproic Acid (Depakote)FDA LinkGeneric
07/2012
1Proto-Oncogene Proteins c-sis (Platelet Derived Growth Factor B)IBA
03/2012
1CollagenIBA
03/2012
1Leptin ReceptorsIBA
03/2012
1Type I Tumor Necrosis Factor ReceptorsIBA
01/2011
1rho-Associated KinasesIBA
09/2010
1Y 27632IBA
09/2010
1CalciumIBA
08/2010
1Transforming Growth Factor beta (TGF-beta)IBA
07/2010

Therapy/Procedure

30Therapeutics
01/2022 - 01/2002
10Cell- and Tissue-Based Therapy (Cell Therapy)
01/2022 - 03/2006
9Transplantation
12/2015 - 07/2002
5Catheters
04/2015 - 04/2002
4Surgical Amputation (Amputations)
04/2015 - 12/2012
3Aftercare (After-Treatment)
01/2022 - 03/2012
3Injections
01/2018 - 04/2002
3Ligation
02/2007 - 03/2006
2Intramuscular Injections
09/2014 - 12/2012
2Hematopoietic Stem Cell Mobilization
07/2014 - 06/2013
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
05/2006 - 09/2004
1Blood Component Removal (Apheresis)
06/2013
1Subcutaneous Injections
01/2013
1Cell Transplantation
07/2012
1Limb Salvage
08/2011